Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682479 | 0.82 | MTNR1A (0.66) | EPHX2MTNR1AMTNR1BDRD2BTK | |
| SCHEMBL29565539 | 0.82 | MTNR1A (0.66) | EPHX2MTNR1AMTNR1BDRD2BTK | |
| SCHEMBL5070808 | 0.80 | EPHX2 (0.38) | EPHX2DRD2CTSKBTKKDM1A | |
| SCHEMBL20262067 | 0.80 | GAA (0.39) | EPHX2DRD2CTSKBTKKDM1A | |
| SCHEMBL9689056 | 0.79 | DRD2 (0.49) | DRD2KMT2A | |
| SCHEMBL9136687 | 0.78 | CA1 (0.64) | EPHX2MTNR1AMTNR1BDRD2BTK | |
| SCHEMBL5722246 | 0.78 | CA1 (0.64) | EPHX2MTNR1AMTNR1BDRD2BTK | |
| SCHEMBL5677299 | 0.78 | CA1 (0.64) | EPHX2MTNR1AMTNR1BDRD2BTK | |
| SCHEMBL9752143 | 0.77 | MTNR1A (0.50) | EPHX2MTNR1AMTNR1BDRD2CTSK | |
| SCHEMBL9752147 | 0.77 | MTNR1A (0.50) | EPHX2MTNR1AMTNR1BDRD2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |