Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985904 | 0.91 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL8985861 | 0.89 | MAPT (0.42) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL9640945 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL9639737 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL9689091 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL3927132 | 0.72 | PDE10A (0.51) | ALDH1A1MAPTLMNARAB9ATDP1 | |
| SCHEMBL1699196 | 0.71 | LMNA (0.55) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL10635762 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL6485115 | 0.70 | PDE10A (0.49) | ALDH1A1MAPTLMNARAB9ATDP1 | |
| SCHEMBL9690882 | 0.69 | MAPT (0.68) | ALDH1A1MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |