Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.48 |
| ▸ | MERTK | Q12866 | 3/20 | 0.48 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 4/20 | 0.41 |
| ▸ | ESRRB | O95718 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069333 | 0.84 | HTR7 (0.59) | HTR7HTR1AMETAP1KDM4ETDP1 | |
| SCHEMBL9689199 | 0.75 | SMN1; SMN2 (0.42) | HTR1AMETAP1KDM4ETDP1ALDH1A1 | |
| 1-Hexanol SCHEMBL9688181 | 0.73 | CASP1 (0.66) | KDM4ETDP1ALDH1A1CETPSMN1; SMN2 | |
| 1-Hexanol SCHEMBL9690248 | 0.72 | CASP1 (0.64) | KDM4ETDP1ALDH1A1CETPSMN1; SMN2 | |
| Dipyridyl SCHEMBL28980115 | 0.69 | KDM4E (0.56) | FLT3TYRO3MERTKGAS6METAP1 | |
| SCHEMBL9226047 | 0.69 | TDP1 (0.60) | METAP1KDM4ETDP1ALDH1A1CYP1A2 | |
| SCHEMBL9069327 | 0.69 | PLD1 (0.58) | HTR7HTR1AKDM4ETDP1PLD1 | |
| Dipyridyl SCHEMBL28135789 | 0.68 | KDM4E (0.64) | METAP1KDM4ETDP1ALDH1A1CYP1A2 | |
| SCHEMBL10974393 | 0.66 | KMT2A (0.60) | HTR7HTR1AKDM4ETDP1PLD1 | |
| SCHEMBL9073239 | 0.66 | HTR7 (0.54) | FLT3TYRO3MERTKGAS6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |