Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690416 | 0.93 | PKM (0.34) | PKMHTTSMN1; SMN2ELANEMEN1 | |
| SCHEMBL9690422 | 0.86 | ELANE (0.39) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL9689615 | 0.79 | ELANE (0.37) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL9432185 | 0.78 | ELANE (0.38) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL9690431 | 0.78 | ELANE (0.38) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL23258853 | 0.76 | ELANE (0.37) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL9431775 | 0.76 | ELANE (0.37) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL25601214 | 0.76 | ELANE (0.37) | ELANEMEN1KMT2AMMP9ALDH1A1 | |
| SCHEMBL9689243 | 0.75 | ELANE (0.43) | ELANEKMT2AMMP9MMP2MMP1 | |
| SCHEMBL9432113 | 0.72 | ELANE (0.41) | ELANEMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481116-A1 | A process for producing halomethylcarbapenems | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-5064954-A | Phosphorylation of hydroxymethylcarbapem and halogenation; bactericides | SHIONOGI & CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |