Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.33 |
| ▸ | GSDMD | P57764 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23467149 | 0.87 | DPP4 (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL17652005 | 0.80 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL1964784 | 0.80 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL1615608 | 0.80 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL20495355 | 0.78 | LMNA (0.39) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL6949926 | 0.78 | LMNA (0.39) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL3200366 | 0.77 | LMNA (0.42) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL31145674 | 0.76 | OR51E2 (0.42) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL18098236 | 0.74 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL14361944 | 0.74 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173112-A | Nonplugging, improved storage stability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-22 | — | — | US | disclosed |