Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351049 | 0.84 | ALDH1A1 (0.41) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL31145674 | 0.82 | OR51E2 (0.42) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL18783157 | 0.78 | SMN1; SMN2 (0.36) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL27530727 | 0.78 | GPR84 (0.48) | LMNACA1CA12CA9GPR84 | |
| SCHEMBL9689376 | 0.78 | LMNA (0.42) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL3056302 | 0.77 | DPP4 (0.34) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL3056305 | 0.77 | GABRR1 (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL18485877 | 0.77 | LMNA (0.33) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL4072000 | 0.76 | — | — | |
| SCHEMBL1964784 | 0.76 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018162554-A1 | BIODEGRADABLE SOLVENT | BASF SE (DE) | 2018-09-13 | — | — | WO | claimed |
| WO-2018162554-A1 | BIODEGRADABLE SOLVENT | BASF SE (DE) | 2018-09-13 | — | — | WO | disclosed |
| CN-101544651-B | Method for synthesizing polysubstitution pyridinone compounds | UNIV EAST CHINA NORMAL | 2011-11-02 | — | — | CN | disclosed |
| CN-101544651-A | Method for synthesizing polysubstitution pyridinone compounds | UNIV EAST CHINA NORMAL | 2009-09-30 | — | — | CN | disclosed |