Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384694 | 0.99 | EGFR (0.43) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9382020 | 0.96 | EGFR (0.43) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9383692 | 0.92 | EGFR (0.45) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9381112 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9380917 | 0.80 | EGFR (0.40) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9382965 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9381382 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHREGFRSRC | |
| SCHEMBL9386041 | 0.68 | DAO (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9686866 | 0.67 | POLB (0.39) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL21333807 | 0.64 | ALDH1A1 (0.47) | ALDH1A1HSD17B10LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079246-A | Antidepressants, anxiolytic agents | BEACHAM GROUP P. L. C. (GB) | 1992-01-07 | — | — | US | disclosed |