Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 2/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689534 | 0.92 | FFAR4 (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CFFAR4 | |
| SCHEMBL10814008 | 0.91 | FFAR4 (0.48) | FFAR4SLC1A5MRGPRX4ALDH1A1GAA | |
| SCHEMBL11169187 | 0.89 | FFAR4 (0.41) | FFAR4SLC1A5MRGPRX4ALDH1A1GAA | |
| SCHEMBL9689738 | 0.85 | CACNA1F (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CFFAR4 | |
| SCHEMBL10818189 | 0.84 | TP53 (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CSLC1A5 | |
| SCHEMBL11009743 | 0.83 | CACNA1F (0.57) | CACNA1FCACNA1DCACNA1SCACNA1CFFAR4 | |
| SCHEMBL10649923 | 0.82 | L3MBTL1 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CFFAR4 | |
| SCHEMBL10646682 | 0.81 | SMYD3 (0.43) | FFAR4SLC1A5MRGPRX4ALDH1A1GAA | |
| SCHEMBL9691796 | 0.80 | HTR6 (0.43) | MRGPRX4GAAL3MBTL1NR4A2MAOB | |
| SCHEMBL11007406 | 0.80 | FFAR4 (0.51) | FFAR4SLC1A5MRGPRX4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071819-B2 | DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |