Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.39 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814008 | 0.95 | FFAR4 (0.48) | FFAR4SLC1A5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL9689636 | 0.92 | CACNA1F (0.45) | FFAR4SLC1A5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL11169187 | 0.90 | FFAR4 (0.41) | FFAR4SLC1A5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL10646682 | 0.88 | SMYD3 (0.43) | FFAR4SLC1A5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL9691796 | 0.88 | HTR6 (0.43) | GAAL3MBTL1MRGPRX4NR4A2MAOB | |
| SCHEMBL9691359 | 0.88 | POLB (0.44) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL10649923 | 0.88 | L3MBTL1 (0.39) | FFAR4SLC1A5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL9691807 | 0.86 | SLC1A5 (0.44) | SLC1A5MRGPRX4 | |
| SCHEMBL10914095 | 0.85 | POLB (0.46) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL9691625 | 0.84 | NR1I2 (0.42) | SLC1A5ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071819-B2 | DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| EP-0288758-B1 | DIHYDROPYRIDINAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0071819-A1 | Dihydropyridines with a positive inotropic activity, their use in pharmaceutical preparations, and processes for their preparation | BAYER AG (DE) | 1983-02-16 | — | — | EP | disclosed |