Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691325 | 0.87 | RAB9A (0.39) | MAPTRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9691855 | 0.85 | XIAP (0.39) | MAPTRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9691327 | 0.85 | MAPT (0.39) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13494020 | 0.81 | MAPT (0.48) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9692016 | 0.81 | RAB9A (0.37) | RAB9ASMN1; SMN2XIAPPOLBNPC1 | |
| SCHEMBL9668631 | 0.78 | MAPT (0.40) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9692047 | 0.72 | KMT2A (0.38) | MAPTRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9689720 | 0.72 | PTPN11 (0.39) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9691344 | 0.71 | MEN1 (0.54) | MAPTRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9691348 | 0.70 | ABCC8 (0.37) | MAPTGAARAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508901-A2 | Alpha-methylene-4-[(phenoxy)methyl)]5-thiazolacetic acid derivatives, process for their preparation, intermediates in this process, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-14 | — | — | EP | disclosed |