SCHEMBL9692016

SCHEMBL9692016

CN(C)C=C(C(=O)O)c1scnc1COc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.37
NPC1 O15118 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
ALOX15 P16050 1/20 0.36
KDR P35968 1/20 0.35
ALOX5 P09917 1/20 0.35
POLB P06746 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
XIAP P98170 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9691643 0.84 RAB9A (0.38) RAB9ANPC1SMN1; SMN2ALOX15KDR
SCHEMBL9689756 0.81 MAPT (0.39) RAB9ANPC1SMN1; SMN2POLBMEN1
SCHEMBL9691325 0.80 RAB9A (0.39) RAB9ANPC1SMN1; SMN2CYP11B1CYP11B2
SCHEMBL9691855 0.78 XIAP (0.39) RAB9ANPC1SMN1; SMN2CYP11B1CYP11B2
SCHEMBL9666877 0.77 SMN1; SMN2 (0.39) RAB9ANPC1SMN1; SMN2ALOX15KDR
SCHEMBL9668730 0.77 KDR (0.39) RAB9ANPC1SMN1; SMN2ALOX15KDR
SCHEMBL9690951 0.69 ALOX15 (0.44) RAB9ANPC1SMN1; SMN2ALOX15POLB
SCHEMBL9581101 0.68 RAB9A (0.37) RAB9ANPC1SMN1; SMN2ALOX5POLB
SCHEMBL9669276 0.68 RAB9A (0.43) RAB9ANPC1SMN1; SMN2POLBXIAP
SCHEMBL9691327 0.65 MAPT (0.39) RAB9ANPC1SMN1; SMN2POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0508901-A2 Alpha-methylene-4-[(phenoxy)methyl)]5-thiazolacetic acid derivatives, process for their preparation, intermediates in this process, their use as fungicides and compositions containing them ROUSSEL UCLAF (FR) 1992-10-14 EP disclosed