Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691086 | 0.80 | KDM4E (0.42) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL7712356 | 0.77 | ALDH1A1 (0.55) | PARP1ALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL3354007 | 0.77 | HAVCR2 (0.43) | XDHCXCR2ALDH1A1HSD17B10HPGD | |
| SCHEMBL9354205 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL9655344 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL1662301 | 0.72 | ALDH1A1 (0.52) | XDHCXCR2NOTUMALDH1A1HSD17B10 | |
| SCHEMBL4471451 | 0.70 | DHFR (0.44) | ALDH1A1BRS3 | |
| SCHEMBL4471447 | 0.70 | KDM4E (0.37) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL11783850 | 0.69 | HSD17B10 (0.58) | NOTUMALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL399518 | 0.69 | HPGD (0.55) | ALDH1A1HSD17B10HPGDALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298134-B1 | AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4965266-A | Antiallergens | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0298134-A1 | AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-01-11 | — | — | EP | disclosed |