Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660927 | 0.89 | NPC1 (0.48) | ADRA2APOLBNPC1KMT2AHPGD | |
| SCHEMBL9661610 | 0.82 | NPC1 (0.49) | ADRA2APOLBNPC1KMT2AHPGD | |
| SCHEMBL9661549 | 0.79 | NPC1 (0.45) | POLBNPC1KMT2AHPGDMEN1 | |
| SCHEMBL9581049 | 0.77 | KMT2A (0.61) | POLBNPC1KMT2AHPGDMEN1 | |
| SCHEMBL9690030 | 0.75 | NPC1 (0.47) | POLBNPC1KMT2AMEN1RAB9A | |
| SCHEMBL9689472 | 0.73 | HPGD (0.52) | POLBNPC1KMT2AHPGDMEN1 | |
| SCHEMBL10839121 | 0.70 | ATM (0.48) | POLBNPC1KMT2AHPGDMEN1 | |
| SCHEMBL17681600 | 0.70 | GAA (0.53) | KMT2AMEN1GAAALDH1A1MCL1 | |
| SCHEMBL9690115 | 0.69 | ADRA2A (0.39) | ADRA2APOLBNPC1KMT2AHPGD | |
| SCHEMBL1107802 | 0.68 | NPC1 (0.41) | POLBNPC1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |