Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690030 | 0.75 | NPC1 (0.47) | ALDH1A1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL9661549 | 0.73 | NPC1 (0.45) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9690119 | 0.73 | ADRA2A (0.49) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9660927 | 0.73 | NPC1 (0.48) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9690724 | 0.73 | POLB (0.44) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9581167 | 0.73 | ALDH1A1 (0.55) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9660439 | 0.71 | HPGD (0.41) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9661610 | 0.71 | NPC1 (0.49) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10389130 | 0.71 | RAPGEF3 (0.42) | GRM4RAPGEF3 | |
| SCHEMBL9660740 | 0.70 | NPC1 (0.41) | HPGDKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |