Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690119 | 0.89 | ADRA2A (0.49) | NPC1KMT2AHPGDALDH1A1ADRA2A | |
| SCHEMBL9661610 | 0.85 | NPC1 (0.49) | NPC1KMT2AHPGDALDH1A1ADRA2A | |
| SCHEMBL9661549 | 0.82 | NPC1 (0.45) | NPC1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL9658734 | 0.77 | HPGD (0.45) | NPC1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL9581049 | 0.77 | KMT2A (0.61) | NPC1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL9690030 | 0.75 | NPC1 (0.47) | NPC1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL9689472 | 0.73 | HPGD (0.52) | NPC1KMT2AHPGDALDH1A1POLB | |
| SCHEMBL3161607 | 0.71 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTADRA2APOLB | |
| SCHEMBL10839121 | 0.70 | ATM (0.48) | NPC1KMT2AHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5745586 | 0.70 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPTADRA2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |