Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690284 | 0.91 | MAPK8 (0.46) | ALOX5APPPARGMEN1KMT2A | |
| SCHEMBL9531469 | 0.86 | PPARG (0.49) | PPARGEDNRB | |
| SCHEMBL9690851 | 0.85 | PPARG (0.44) | ALOX5APPPARGKDM4ERCE1CNR1 | |
| SCHEMBL9532793 | 0.81 | KDM4E (0.39) | KDM4ERCE1EDNRBCNR1 | |
| SCHEMBL9531997 | 0.77 | PPARG (0.45) | PPARGCNR1 | |
| SCHEMBL9531841 | 0.76 | PPARG (0.52) | PPARG | |
| SCHEMBL9536684 | 0.75 | MAPK8 (0.55) | PPARG | |
| SCHEMBL1890010 | 0.75 | PPARG (0.48) | ALOX5APPPARGFFAR1AKR1B1CNR1 | |
| SCHEMBL9530978 | 0.73 | PPARG (0.51) | PPARG | |
| SCHEMBL9530948 | 0.73 | KDM4E (0.43) | PPARGKDM4EEDNRBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |