Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE6D | O43924 | 2/20 | 0.32 |
| ▸ | PDE6A | P16499 | 2/20 | 0.32 |
| ▸ | PDE6G | P18545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689111 | 0.71 | KDM4E (0.46) | KDM4EHTTLMNAMAPTHPGD | |
| SCHEMBL18323596 | 0.69 | KDM4E (0.50) | CYP3A4KDM4ECYP1A2HTTALDH1A1 | |
| SCHEMBL9691180 | 0.69 | HPGD (0.56) | CYP3A4CYP2C19CYP2C9KDM4ECYP1A2 | |
| SCHEMBL9690087 | 0.69 | CYP2A6 (0.38) | CYP2A6CYP3A4CYP2C19CYP2B6CYP2D6 | |
| SCHEMBL9690839 | 0.67 | HPGD (0.41) | CYP3A4CYP2C19CYP2C9KDM4ECYP1A2 | |
| SCHEMBL9689092 | 0.65 | GABRA1 (0.37) | CYP2C19CYP2C9KDM4ECYP1A2ALDH1A1 | |
| SCHEMBL3610326 | 0.64 | CYP2A6 (1.00) | CYP2A6CYP3A4CYP2C19CYP2B6CYP2D6 | |
| SCHEMBL9690969 | 0.63 | KDM4E (0.54) | CYP3A4KDM4ECYP1A2ALDH1A1LMNA | |
| SCHEMBL722595 | 0.63 | CYP2A6 (0.56) | CYP2A6CYP3A4CYP2C19CYP2B6CYP2D6 | |
| SCHEMBL1665000 | 0.62 | CYP1A2 (0.44) | KDM4ECYP1A2HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060843-A | TRIAZOLOPYRIDAZINE DERIVATES | RHONE POULENC AGROCHIMIE (FR) | 1992-05-06 | — | — | CN | disclosed |
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |