Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692327 | 0.79 | HTT (0.43) | HTTMMP2MMP3MMP9MEN1 | |
| SCHEMBL11153661 | 0.77 | EPHX1 (0.39) | — | |
| SCHEMBL11163625 | 0.76 | EPHX1 (0.36) | — | |
| SCHEMBL11164487 | 0.72 | EPHX1 (0.38) | — | |
| SCHEMBL320551 | 0.72 | HCAR3 (0.41) | HTTMEN1KMT2A | |
| SCHEMBL18338919 | 0.71 | OPRM1 (0.47) | MEN1KMT2A | |
| SCHEMBL9692277 | 0.71 | CYP3A4 (0.36) | MEN1KMT2A | |
| SCHEMBL9691992 | 0.70 | KMT2A (0.51) | HTTMEN1KMT2A | |
| SCHEMBL14967132 | 0.70 | HTT (0.41) | HTTMEN1KMT2A | |
| SCHEMBL9692240 | 0.69 | MEN1 (0.43) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |