Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474726 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL9692476 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL9824929 | 0.78 | KCNH2 (0.49) | KDM4EDRD2HTR2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9690403 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL9690345 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9690397 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1ATM | |
| SCHEMBL9691961 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9691955 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL8194970 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1ATM | |
| SCHEMBL8195860 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |
| US-5112855-A | Nootropic Agents | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-4957928-A | NOOTROPIC AGENTS, COGNITION ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |