Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690700 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CHRNB4CHRNA3NPSR1SMN1; SMN2 | |
| SCHEMBL9581166 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CHRNB4CHRNA3NPSR1SMN1; SMN2 | |
| SCHEMBL6228628 | 0.81 | PKM (0.38) | ALDH1A1PKMTSHRCHRNB4CHRNA3 | |
| SCHEMBL9690026 | 0.81 | TSHR (0.38) | ALDH1A1PKMTSHRSMN1; SMN2NPC1 | |
| SCHEMBL9689560 | 0.81 | ALDH1A1 (0.36) | ALDH1A1NPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11747051 | 0.80 | ALDH1A1 (0.53) | ALDH1A1NPSR1SMN1; SMN2NPC1TP53 | |
| SCHEMBL9689432 | 0.78 | ALDH1A1 (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL9690773 | 0.78 | GRIN2D (0.37) | ALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL9690093 | 0.77 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9689448 | 0.76 | ALDH1A1 (0.35) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |