Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690093 | 0.82 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9690716 | 0.78 | ALDH1A1 (0.39) | ALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL9690700 | 0.78 | ALDH1A1 (0.39) | ALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL9581166 | 0.78 | ALDH1A1 (0.39) | ALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL11747051 | 0.76 | ALDH1A1 (0.53) | ALDH1A1NPSR1SMN1; SMN2NOS3NOS1 | |
| SCHEMBL9689448 | 0.75 | ALDH1A1 (0.35) | ALDH1A1NPSR1 | |
| SCHEMBL9690768 | 0.75 | ALDH1A1 (0.50) | ALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL9689432 | 0.74 | ALDH1A1 (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL9689560 | 0.74 | ALDH1A1 (0.36) | ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL9690026 | 0.74 | TSHR (0.38) | ALDH1A1SMN1; SMN2MAPTHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |