Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690703 | 0.83 | ALDH1A1 (0.47) | ALDH1A1NPSR1MAPTSMN1; SMN2GAA | |
| SCHEMBL9690716 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NPSR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9581166 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NPSR1TAAR1MAPTSMN1; SMN2 | |
| SCHEMBL9690700 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NPSR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9690773 | 0.75 | GRIN2D (0.37) | ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL11747051 | 0.74 | ALDH1A1 (0.53) | ALDH1A1NPSR1TAAR1MAPTSMN1; SMN2 | |
| SCHEMBL9660134 | 0.74 | HRH4 (0.47) | ALDH1A1NPSR1LRRK2MEN1KMT2A | |
| SCHEMBL9689448 | 0.73 | ALDH1A1 (0.35) | ALDH1A1NPSR1 | |
| SCHEMBL9689560 | 0.72 | ALDH1A1 (0.36) | ALDH1A1NPSR1TAAR1SMN1; SMN2 | |
| SCHEMBL9689432 | 0.72 | ALDH1A1 (0.36) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |