Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9693049 | 0.99 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9316225 | 0.93 | ALDH1A1 (0.55) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9096780 | 0.92 | ALDH1A1 (0.54) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9693034 | 0.89 | KCNH2 (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9693064 | 0.89 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9692567 | 0.88 | TOP2A (0.56) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| Bromide SCHEMBL9845004 | 0.88 | TOP2A (0.56) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7821381 | 0.87 | KDM4E (0.69) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10400523 | 0.86 | KDM4E (0.67) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL8094873 | 0.85 | TOP2A (0.60) | TOP2ATOP2BKCNH2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091384-A | ANTI-BACTERIAL QUINOLONE- AND NAPHTHYRIDONE-CARBOXYLIC ACID COMPOUNDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-02-25 | — | — | US | disclosed |
| EP-0424850-A1 | Quinolone compounds and a process for their preparation | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-05-02 | — | — | EP | disclosed |