Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691008 | 0.85 | KCNH2 (0.52) | PKMMAPTTP53POLBALDH1A1 | |
| SCHEMBL9809684 | 0.84 | MAPT (0.54) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL9809681 | 0.82 | OPRM1 (0.56) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL9809664 | 0.82 | MAPT (0.54) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL9809657 | 0.82 | OPRM1 (0.61) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL9809676 | 0.82 | OPRM1 (0.58) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL9809635 | 0.82 | GAA (0.53) | OPRM1TMEM97SIGMAR1CYP3A4OPRK1 | |
| SCHEMBL9809660 | 0.80 | OPRM1 (0.54) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL9809729 | 0.80 | ALDH1A1 (0.61) | OPRM1TMEM97SIGMAR1PKMCYP3A4 | |
| SCHEMBL7171733 | 0.74 | KCNH2 (0.74) | OPRM1TMEM97SIGMAR1CYP3A4OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298134-B1 | AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4965266-A | Antiallergens | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0298134-A1 | AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-01-11 | — | — | EP | disclosed |