Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | APP | P05067 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809676 | 0.90 | OPRM1 (0.58) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809684 | 0.88 | MAPT (0.54) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809681 | 0.88 | OPRM1 (0.56) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809660 | 0.88 | OPRM1 (0.54) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809664 | 0.88 | MAPT (0.54) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809729 | 0.87 | ALDH1A1 (0.61) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809635 | 0.87 | GAA (0.53) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9809723 | 0.83 | APP (0.65) | TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL9690990 | 0.82 | OPRM1 (0.57) | OPRM1TMEM97SIGMAR1APPOPRK1 | |
| SCHEMBL15329262 | 0.79 | ESRRG (0.60) | CYP3A4CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071850-A | Cardiovascular disorders | PIERRE FABRE MEDICAMENT (FR) | 1991-12-10 | — | — | US | disclosed |