Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036910 | 1.00 | THRB (0.48) | THRBMEN1KMT2AHTTMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL2799781 | 0.89 | ALDH1A1 (0.43) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL173351 | 0.88 | TSHR (0.41) | THRBKMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL57345 | 0.85 | THRB (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9067424 | 0.85 | THRB (0.46) | THRBMEN1KMT2AHTTMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL999353 | 0.84 | TSHR (0.57) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL111960 | 0.84 | THRB (0.68) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4454310 | 0.84 | TSHR (0.65) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL6895196 | 0.84 | THRB (0.53) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL8815469 | 0.82 | MEN1 (0.44) | THRBMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147903-A | DENTAL MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-15 | — | — | US | disclosed |
| US-4174152-A | Electrochromic devices with polymeric electrolytes | AMERICAN CYANAMID COMPANY (US) | 1979-11-13 | — | — | US | disclosed |