SCHEMBL9691776

SCHEMBL9691776

C=CCOS(=O)(=O)C(F)(F)F.[Pd].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.38
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 2/20 0.36
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ALOX15 P16050 1/20 0.32
PTPRC P08575 1/20 0.31
ALDH1A1 P00352 2/20 0.31
CDK1 P06493 1/20 0.31
CDK2 P24941 1/20 0.31
KDR P35968 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31375314 0.82 CA2 (0.35) CA2CA1CA9
SCHEMBL3267896 0.80 CASP1 (0.35) CA2TDP1ALDH1A1KDM4E
SCHEMBL37730 0.80 CA2 (0.37) CA2CA1CA9
SCHEMBL27810105 0.78 CA2 (0.35) CA2CA1CA9
SCHEMBL27540621 0.78 CA2 (0.35) CA2CA1CA9
SCHEMBL30865709 0.78 CA2 (0.35) CA2CA1CA9
Trifluoromethanesulfonic Acid SCHEMBL1450924 0.75 GPR3 (0.40) CYP3A4TDP1RAB9AESR1ESR2
Trifluoromethanesulfonic Acid SCHEMBL9691783 0.75 GPR3 (0.40) CYP3A4TDP1RAB9AESR1ESR2
SCHEMBL9691607 0.74
SCHEMBL9703417 0.74 C5AR1 (0.43) CA2CYP3A4CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153692-B1 METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-29 EP disclosed
EP-0153692-A2 Method for isomerization a glycidate derivative SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-09-04 EP disclosed