Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.78 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693445 | 0.88 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL9692111 | 0.86 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9693383 | 0.85 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9692011 | 0.85 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9691765 | 0.84 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9693319 | 0.84 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9694200 | 0.82 | PDE3B (0.77) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9693683 | 0.81 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9693701 | 0.80 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL9694150 | 0.79 | PDE3B (0.61) | PDE3BPDE3APDE2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-B1 | AMINOIMIDAZOQUINOLINE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |