SCHEMBL9692289

SCHEMBL9692289

CC(C)(C)OC(=O)N(C(=O)OCc1ccc([N+](=O)[O-])cc1)[C@@H](CCCCN)C(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.37
▸ ALDH1A1 P00352 4/20 0.35
▸ MAPT P10636 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ NR1D1 P20393 1/20 0.35
▸ DPP8 Q6V1X1 1/20 0.35
▸ DPP9 Q86TI2 1/20 0.35
▸ TPSAB1 Q15661 2/20 0.34
▸ TPSD1 Q9BZJ3 2/20 0.34
▸ TPSG1 Q9NRR2 2/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ EPOR P19235 1/20 0.33
▸ TGM2 P21980 1/20 0.33
▸ PDF Q9HBH1 1/20 0.33
▸ MC4R P32245 1/20 0.33
▸ GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30605860 0.86 EPOR (0.42) HTR2AALDH1A1TPSAB1TPSD1TPSG1
SCHEMBL7959193 0.83 GAA (0.43) HTR2AALDH1A1MAPTPDFGAA
SCHEMBL4391556 0.83 GAA (0.43) HTR2AALDH1A1MAPTPDFGAA
SCHEMBL4357291 0.78 EPOR (0.46) HTR2AALDH1A1RAB9AEPORMC4R
SCHEMBL10432184 0.77 MC4R (0.47) RAB9AEPORTGM2MC4R
SCHEMBL7785339 0.76 TPSAB1 (0.47) MAPTTPSAB1TPSD1TPSG1EPOR
SCHEMBL5692891 0.75 EPOR (0.55) MAPTTPSAB1TPSD1TPSG1EPOR
SCHEMBL375887 0.74 TPSAB1 (0.53) MAPTTPSAB1TPSD1TPSG1EPOR
SCHEMBL4150947 0.74 TPSAB1 (0.53) MAPTTPSAB1TPSD1TPSG1EPOR
SCHEMBL3820596 0.74 TPSAB1 (0.53) MAPTTPSAB1TPSD1TPSG1EPOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0165492-B1 PROCESS FOR MANUFACTURING PREPARATIONS PROMOTING WOUND HEALING, AND SUCH PREPARATIONS BERLIN-CHEMIE Aktiengesellschaft (DE) 1992-10-14 — — EP disclosed
EP-0165492-A2 Process for manufacturing preparations promoting wound healing, and such preparations BERLIN-CHEMIE Aktiengesellschaft (DE) 1985-12-27 — — EP disclosed
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