Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 12/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692777 | 0.97 | ALDH1A1 (0.38) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9502413 | 0.91 | CETP (0.42) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9692530 | 0.91 | CETP (0.42) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9502962 | 0.91 | CETP (0.42) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9502223 | 0.85 | CETP (0.43) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9503044 | 0.85 | CETP (0.43) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9502277 | 0.85 | MAPT (0.35) | HDAC8ALDH1A1HTTMAPTFAAH | |
| SCHEMBL9503970 | 0.84 | MAPT (0.35) | HDAC8ALDH1A1MAPT | |
| SCHEMBL9503866 | 0.84 | HDAC3 (0.38) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL9506112 | 0.83 | ACAT1 (0.39) | HDAC3ALDH1A1HTTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |