Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502277 | 0.99 | MAPT (0.35) | MAPTHDAC8POLBALDH1A1NAMPT | |
| SCHEMBL9503117 | 0.85 | ACAT1 (0.38) | MAPTPOLBACAT1 | |
| SCHEMBL9503202 | 0.85 | KMT2A (0.36) | MAPTALDH1A1ACAT1 | |
| SCHEMBL9692984 | 0.85 | ACAT1 (0.38) | MAPTPOLBACAT1 | |
| SCHEMBL9505639 | 0.83 | HPGD (0.34) | MAPTHDAC8POLBACAT1NAMPT | |
| SCHEMBL9692777 | 0.83 | ALDH1A1 (0.38) | MAPTHDAC8ALDH1A1NAMPT | |
| SCHEMBL9675548 | 0.78 | MAPT (0.40) | MAPTPOLBALDH1A1NAMPT | |
| SCHEMBL9502413 | 0.77 | CETP (0.42) | HDAC8ALDH1A1ACAT1 | |
| SCHEMBL9692530 | 0.77 | CETP (0.42) | HDAC8ALDH1A1ACAT1 | |
| SCHEMBL9502962 | 0.77 | CETP (0.42) | HDAC8ALDH1A1ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |