Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20829222 | 1.00 | DRD2 (0.44) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL4732321 | 0.83 | DRD2 (0.51) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL14098286 | 0.82 | DRD2 (0.39) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL14098274 | 0.80 | HTR7 (0.39) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL2974509 | 0.78 | ACHE (0.41) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL11009217 | 0.77 | LMNA (0.40) | DRD2HRH1HTR2CTP53CYP3A4 | |
| SCHEMBL11573922 | 0.77 | ACHE (0.48) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL9693133 | 0.77 | HTR2A (0.45) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL8169090 | 0.77 | DRD2 (0.48) | DRD2HRH1HTR2CDRD4TP53 | |
| SCHEMBL9873313 | 0.77 | DRD2 (0.41) | DRD2HRH1HTR2CDRD4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686201-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-07-29 | — | — | EP | disclosed |