Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 15/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693341 | 1.00 | HPGD (0.52) | HPGDALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL10753482 | 0.80 | TSHR (0.44) | HPGDALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL10753480 | 0.80 | TSHR (0.44) | HPGDALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL9691948 | 0.80 | HPGD (0.51) | HPGDALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL9691943 | 0.80 | HPGD (0.51) | HPGDALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL9693493 | 0.78 | MAPT (0.51) | HPGDALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL9693489 | 0.78 | MAPT (0.51) | HPGDALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL10754644 | 0.77 | ALDH1A1 (0.47) | HPGDALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL10754642 | 0.77 | ALDH1A1 (0.47) | HPGDALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL44794 | 0.75 | HPGD (0.64) | HPGDALDH1A1MAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-B1 | AMINOIMIDAZOQUINOLINE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4701459-A | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |