Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693632 | 0.84 | GAA (0.36) | GAAADRA2ANISCHMEN1KMT2A | |
| SCHEMBL9693373 | 0.81 | ADRA2A (0.35) | GAAADRA2ANISCHMEN1KMT2A | |
| SCHEMBL9163076 | 0.79 | GAA (0.38) | GAAADRA2ANISCHMEN1KMT2A | |
| SCHEMBL9693427 | 0.78 | GAA (0.35) | GAAADRA2ANISCH | |
| SCHEMBL4370549 | 0.76 | ADRA2A (0.37) | GAAADRA2ANISCHMEN1KMT2A | |
| SCHEMBL9597453 | 0.75 | CYP3A4 (0.36) | GAA | |
| SCHEMBL1363366 | 0.70 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL7044026 | 0.68 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL1362959 | 0.64 | PIK3CD (0.39) | PIK3CDMEN1KMT2A | |
| SCHEMBL10657841 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-B1 | AMINOIMIDAZOQUINOLINE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4701459-A | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4668686-A | 1,3-DIHYDRO-2H-IMIDAZO/4,5-B/QUINOLINE-2-ONES | BRISTOL-MYERS COMPANY (US) | 1987-05-26 | — | — | US | disclosed |