SCHEMBL1363366

SCHEMBL1363366

CC(C)CN1C(=O)NC(=O)C1S

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 3/20 0.41
PDE4B Q07343 1/20 0.33
PDE7A Q13946 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044026 0.78 PIK3CD (0.42) PIK3CDPDE4BPDE7A
SCHEMBL1362959 0.77 PIK3CD (0.39) PIK3CDPDE4BPDE7A
SCHEMBL1362856 0.73 GAA (0.31)
SCHEMBL1363459 0.71 GAA (0.46)
SCHEMBL9693393 0.70 PIK3CD (0.33) PIK3CD
SCHEMBL1363519 0.64 F2 (0.37) PIK3CDPDE4BPDE7A
SCHEMBL1363109 0.64
SCHEMBL4738231 0.64
SCHEMBL24403839 0.63 PIK3CD (0.35) PIK3CDPDE4BPDE7A
SCHEMBL11642296 0.63 ALDH1A1 (0.36) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8066977-B2 Agent for permanent hair waving containing heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-11-29 US disclosed
EP-1883454-B1 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2009-11-04 EP disclosed
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound SHOWA DENKO K.K. (JP) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound NSD3, WNT3, MSRB3 PIK3CD 4863/4885PDE4B 4539/4885PDE7A 3788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.