Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693136 | 0.82 | HTR2C (0.55) | KDM1AHTR2CSLC6A3HTR2A | |
| SCHEMBL17425315 | 0.80 | TBXAS1 (0.56) | TBXAS1KDM1AHTR2CTBXA2R | |
| SCHEMBL11611768 | 0.78 | HTR2C (0.44) | TBXAS1HTR2CSLC6A3TBXA2RHTR2A | |
| SCHEMBL17425316 | 0.76 | TBXAS1 (0.55) | TBXAS1KDM1AHTR2CSLC6A3TBXA2R | |
| SCHEMBL6774962 | 0.76 | HTR2A (0.40) | TBXAS1HTR2CTBXA2RHTR2AHRH1 | |
| SCHEMBL9691458 | 0.74 | GAA (0.58) | KDM1AHTR2CSLC6A3TBXA2R | |
| SCHEMBL9693300 | 0.74 | KDM1A (0.40) | TBXAS1KDM1AHTR2CSLC6A3 | |
| SCHEMBL7528263 | 0.74 | MAPT (0.47) | KDM1AATM | |
| SCHEMBL1366717 | 0.74 | TBXAS1 (0.55) | TBXAS1KDM1ATBXA2R | |
| SCHEMBL25680730 | 0.73 | TBXAS1 (0.45) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141960-A | Central nervous system disorders | G. D. SEARLE & CO. (US) | 1992-08-25 | — | — | US | disclosed |