Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248431 | 0.85 | HTR2C (0.64) | HTR2CSLC6A3ACP3RETHTR2A | |
| SCHEMBL9693397 | 0.82 | TBXAS1 (0.46) | HTR2CSLC6A3KDM1AHTR2A | |
| SCHEMBL9691458 | 0.81 | GAA (0.58) | HTR2CSLC6A3KDM1AALDH1A1KMT2A | |
| SCHEMBL9693300 | 0.81 | KDM1A (0.40) | HTR2CSLC6A3KDM1AALDH1A1SCN3A | |
| SCHEMBL7528263 | 0.81 | MAPT (0.47) | KDM1AKMT2ALMNAGAAMEN1 | |
| SCHEMBL7144293 | 0.81 | SCN3A (0.56) | KDM1AHTTALDH1A1KMT2ASCN3A | |
| SCHEMBL7144288 | 0.81 | SCN3A (0.56) | KDM1AHTTALDH1A1KMT2ASCN3A | |
| Hydrochloric Acid SCHEMBL195248 | 0.80 | SCN3A (0.55) | KDM1AHTTALDH1A1KMT2ASCN3A | |
| SCHEMBL5193757 | 0.78 | ALDH1A1 (0.58) | HTTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL9693099 | 0.78 | KDM1A (0.44) | HTR2CSLC6A3KDM1ARETHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141960-A | Central nervous system disorders | G. D. SEARLE & CO. (US) | 1992-08-25 | — | — | US | claimed |
| US-5141960-A | Central nervous system disorders | G. D. SEARLE & CO. (US) | 1992-08-25 | — | — | US | disclosed |