Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PPIA | P62937 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254514 | 0.83 | MAPT (0.53) | MAPTBCHEACHEKMT2APPIA | |
| SCHEMBL9693099 | 0.82 | KDM1A (0.44) | KDM1AKMT2AMEN1ATMHSD17B10 | |
| SCHEMBL28621243 | 0.81 | BCHE (0.51) | MAPTBCHEACHEKMT2APPIA | |
| SCHEMBL9693136 | 0.81 | HTR2C (0.55) | KDM1AKMT2AMEN1LMNAGAA | |
| SCHEMBL7435438 | 0.79 | BCHE (0.49) | MAPTBCHEACHEKMT2APPIA | |
| Hydrochloric Acid SCHEMBL9651566 | 0.77 | BCHE (0.47) | MAPTBCHEACHEKMT2APPIA | |
| SCHEMBL7439749 | 0.75 | POLB (0.50) | MAPTBCHEACHEKMT2AMEN1 | |
| SCHEMBL5525117 | 0.75 | KMT2A (0.59) | MAPTKMT2APPIAHDAC3HDAC4 | |
| SCHEMBL9693126 | 0.74 | KDM1A (0.38) | KDM1A | |
| SCHEMBL9693397 | 0.74 | TBXAS1 (0.46) | KDM1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777680-B1 | UROKINASE RECEPTOR LIGANDS | CHIRON CORP (US) | 2002-03-20 | — | — | EP | disclosed |