Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468250 | 0.88 | TP53 (0.59) | HDAC6HDAC1MEN1TP53PABPC1 | |
| SCHEMBL9390726 | 0.84 | HDAC6 (0.56) | HDAC6HDAC1MEN1TP53PABPC1 | |
| SCHEMBL9390733 | 0.83 | LMNA (0.48) | HDAC6HDAC1LTA4HPPARGCYP11B1 | |
| SCHEMBL9302460 | 0.82 | HDAC1 (0.71) | HDAC6HDAC1CYP11B1CYP11B2HTT | |
| SCHEMBL10467889 | 0.82 | SMN1; SMN2 (0.59) | HDAC6HDAC1TP53LTA4HPPARG | |
| SCHEMBL13508711 | 0.80 | CYP11B1 (0.65) | LTA4HKDM4CCYP11B1CYP11B2HTT | |
| SCHEMBL27441902 | 0.80 | LTA4H (0.46) | HDAC6HDAC1LTA4HKDM4CCYP11B1 | |
| SCHEMBL31229302 | 0.79 | CYP11B1 (0.66) | MEN1KMT2ALTA4HKDM4CCYP11B1 | |
| SCHEMBL10467940 | 0.79 | HPGD (0.48) | SMN1; SMN2LMNA | |
| SCHEMBL26704721 | 0.79 | CYP11B1 (0.68) | LTA4HKDM4CCYP11B1CYP11B2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |