SCHEMBL9694374

SCHEMBL9694374

COc1nc(OC)nc(Oc2cccnc2C(=O)OCc2cccc(Cl)c2)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
KMT2A Q03164 2/20 0.42
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
HTT P42858 1/20 0.41
PPIF P30405 1/20 0.41
CTSA P10619 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
SGMS2 Q8NHU3 1/20 0.40
SMARCA2 P51531 1/20 0.40
POLB P06746 1/20 0.40
ENPP2 Q13822 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9692112 0.92 CTSA (0.49) L3MBTL1KDM4ELMNAMAPTHPGD
SCHEMBL9693873 0.81 NPSR1 (0.53) L3MBTL1CTSASMN1; SMN2
SCHEMBL732099 0.80 CTSA (0.54) L3MBTL1CTSARAB9ASMN1; SMN2
SCHEMBL9693386 0.77 MMP1 (0.51) L3MBTL1KDM4ELMNAMAPTHPGD
SCHEMBL8882254 0.74 KDM4E (0.53) KDM4EMAPTMMP1MMP2MMP9
SCHEMBL9693462 0.74 CTSA (0.57) L3MBTL1HTTCTSASMN1; SMN2
SCHEMBL9384848 0.73 KDM4E (0.45) L3MBTL1KDM4EMAPTCTSA
SCHEMBL9682835 0.73 KMT2A (0.43) KMT2APOLBSMN1; SMN2MEN1
SCHEMBL8380211 0.72 L3MBTL1 (0.44) L3MBTL1KDM4ELMNAMAPTKMT2A
SCHEMBL7846224 0.72 CTSA (0.55) CTSASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249707-B1 PICOLINIC ACID DERIVATIVES AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-03-11 EP disclosed
US-4931087-A Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-06-05 US disclosed
US-4832729-A Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-05-23 US disclosed
EP-0249707-A1 Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 EP disclosed