Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19808952 | 0.83 | TDP1 (0.59) | POLBKMT2AMAOBL3MBTL1KDM4E | |
| SCHEMBL9694374 | 0.77 | L3MBTL1 (0.44) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL14284363 | 0.76 | NPC1 (0.60) | POLBKMT2AMAOBMEN1KDM4E | |
| SCHEMBL9692112 | 0.76 | CTSA (0.49) | MMP1MMP2MMP9MMP12L3MBTL1 | |
| SCHEMBL8882076 | 0.75 | RXRA (0.56) | KMT2AMEN1HPGDRXRARXRB | |
| SCHEMBL1129557 | 0.75 | LMNA (0.66) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL26170243 | 0.74 | EGLN1 (0.58) | POLBMAOAMAOBKDM4ELMNA | |
| SCHEMBL10891480 | 0.74 | SERPINE1 (0.58) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL28566933 | 0.73 | POLB (0.65) | POLBKMT2AMAOBMEN1L3MBTL1 | |
| SCHEMBL27577784 | 0.73 | HCAR2 (0.64) | MMP1MMP2MMP9MMP12HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249707-B1 | PICOLINIC ACID DERIVATIVES AND HERBICIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4931087-A | Picolinic acid derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4832729-A | Picolinic acid derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |