Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749399 | 0.89 | ALDH1A1 (0.62) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11610529 | 0.89 | RAB9A (0.69) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11616542 | 0.89 | RAB9A (0.69) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11753370 | 0.87 | RAB9A (0.68) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5687511 | 0.87 | RARB (1.00) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8534144 | 0.87 | RARB (1.00) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL9734086 | 0.87 | RARB (1.00) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8371650 | 0.87 | RARB (1.00) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL9817507 | 0.87 | RARB (1.00) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11612813 | 0.87 | RAB9A (0.67) | RARBRAB9ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124068-A | Liquid crystal displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-06-23 | — | — | US | disclosed |
| US-5043093-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0215800-A1 | PYRIMIDINES. | MERCK PATENT GMBH (DE) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986004060-A1 | PYRIMIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-17 | — | — | WO | disclosed |