Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850104 | 0.79 | ALDH1A1 (0.54) | MAPTSMN1; SMN2RARBMEN1ALDH1A1 | |
| SCHEMBL10606383 | 0.78 | GCGR (0.49) | MAPTSMN1; SMN2TLR8MEN1ALDH1A1 | |
| SCHEMBL20874436 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2RARBCYP4A11CYP4F2 | |
| SCHEMBL29116868 | 0.76 | GCGR (0.48) | MAPTSMN1; SMN2TLR8NPC1RAB9A | |
| SCHEMBL4188800 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2RARBCYP4A11CYP4F2 | |
| SCHEMBL2401275 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2RARBCYP4A11CYP4F2 | |
| SCHEMBL4178997 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2RARBCYP4A11CYP4F2 | |
| SCHEMBL9695133 | 0.76 | RARB (0.73) | MAPTSMN1; SMN2TLR8MGLLRARB | |
| SCHEMBL9696525 | 0.76 | RARB (0.73) | MAPTSMN1; SMN2TLR8MGLLRARB | |
| SCHEMBL9693690 | 0.76 | RARB (0.73) | MAPTSMN1; SMN2TLR8MGLLRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124068-A | Liquid crystal displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-06-23 | — | — | US | disclosed |
| US-5043093-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0215800-B1 | PYRIMIDINES | MERCK PATENT GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |
| EP-0215800-A1 | PYRIMIDINES. | MERCK PATENT GMBH (DE) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986004060-A1 | PYRIMIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-17 | — | — | WO | disclosed |