Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29116868 | 0.98 | GCGR (0.48) | GCGRHTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9850104 | 0.86 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1MAPTPTGS2 | |
| SCHEMBL10555514 | 0.82 | GCGR (0.52) | GCGRHTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10559262 | 0.81 | RARB (0.54) | GCGRRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL29116869 | 0.80 | GCGR (0.51) | GCGRHTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9815158 | 0.79 | MGLL (0.44) | GCGRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9694782 | 0.78 | MAPT (0.50) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL28827858 | 0.78 | RAB9A (0.46) | GCGRHTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8405040 | 0.76 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2NPC1MAPTPTGS2 | |
| SCHEMBL8405038 | 0.76 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2NPC1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126949-B1 | FLUORINE-CONTAINING PYRIMIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |