Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694982 | 1.00 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL9302114 | 0.72 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| Phenanthrene SCHEMBL28833030 | 0.67 | ALDH1A1 (0.44) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL28485903 | 0.66 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL21724095 | 0.65 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL7113263 | 0.65 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL3630843 | 0.64 | SLC6A3 (0.44) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL25155178 | 0.63 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL31513789 | 0.63 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL30344744 | 0.63 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475627-A1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-03-18 | — | — | EP | disclosed |