Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604766 | 0.76 | SLC6A1 (0.49) | PLA2G1BATG4BSLC6A1SLC6A12SLC6A11 | |
| SCHEMBL4443505 | 0.76 | SLC6A1 (0.49) | PLA2G1BATG4BSLC6A1SLC6A12SLC6A11 | |
| SCHEMBL3416558 | 0.76 | SLC6A1 (0.49) | PLA2G1BATG4BSLC6A1SLC6A12SLC6A11 | |
| SCHEMBL9694982 | 0.72 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL9694987 | 0.72 | SLC6A3 (0.41) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL6360946 | 0.70 | NR3C1 (0.43) | SLC6A4SLC6A2PLA2G1BATG4BKDM4E | |
| SCHEMBL4668723 | 0.70 | NR3C1 (0.43) | SLC6A4SLC6A2PLA2G1BATG4BKDM4E | |
| SCHEMBL4669632 | 0.70 | NR3C1 (0.43) | SLC6A4SLC6A2PLA2G1BATG4BKDM4E | |
| SCHEMBL4443441 | 0.70 | NR3C1 (0.43) | SLC6A4SLC6A2PLA2G1BATG4BKDM4E | |
| SCHEMBL4669637 | 0.70 | NR3C1 (0.43) | SLC6A4SLC6A2PLA2G1BATG4BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369109-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0475627-B1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEM RES (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5276154-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0475627-A1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-03-18 | — | — | EP | disclosed |