Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.45 |
| ▸ | PPARA | Q07869 | 12/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695301 | 0.85 | PPARA (0.45) | PPARGPPARACTRCMEN1KMT2A | |
| SCHEMBL9696796 | 0.84 | PPARG (0.63) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9614239 | 0.84 | PPARG (0.63) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9696319 | 0.81 | PPARG (0.61) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9613840 | 0.78 | PPARG (0.59) | PPARGPPARACTRCMEN1RAB9A | |
| SCHEMBL9614213 | 0.77 | PPARA (0.56) | PPARGPPARACTRCMEN1RAB9A | |
| SCHEMBL9696474 | 0.77 | PPARG (0.56) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9614218 | 0.76 | PPARA (0.73) | PPARGPPARA | |
| SCHEMBL9614193 | 0.76 | PPARA (0.73) | PPARGPPARA | |
| SCHEMBL9696941 | 0.76 | PPARG (0.48) | PPARGPPARASLC6A9CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |