Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9419903 | 0.93 | TSHR (0.42) | LMNATSHRSLC34A1KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL28203319 | 0.89 | SLC34A1 (0.47) | LMNATSHRSLC34A1KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL8740021 | 0.85 | SLC34A1 (0.50) | LMNATSHRSLC34A1TYMS | |
| Phosphoric Acid SCHEMBL27922068 | 0.85 | TSHR (0.42) | LMNATSHRSLC34A1TYMS | |
| Phosphoric Acid SCHEMBL359167 | 0.85 | TSHR (0.42) | LMNATSHRSLC34A1TYMS | |
| Phosphoric Acid SCHEMBL11212324 | 0.85 | TSHR (0.42) | LMNATSHRSLC34A1TYMSFDPS | |
| Phosphoric Acid SCHEMBL9680822 | 0.85 | SLC34A1 (0.50) | LMNATSHRSLC34A1TYMS | |
| Phosphoric Acid SCHEMBL31519804 | 0.85 | TSHR (0.42) | LMNATSHRSLC34A1TYMS | |
| Phosphoric Acid SCHEMBL28118217 | 0.83 | LMNA (0.35) | LMNASLC34A1KDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL16926985 | 0.81 | SLC34A1 (0.57) | LMNATSHRSLC34A1KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106621-A | Derived from pineapple plant stems; for debridement of burn tissue | ROWAN ANDREW D (GB) | 1992-04-21 | — | — | US | disclosed |