Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694749 | 0.94 | ALOX5 (0.65) | ALOX5ADRB2ADRB1ADRB3HTT | |
| SCHEMBL9696408 | 0.85 | ALOX5 (0.62) | ALOX5ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL566990 | 0.83 | MAOB (0.60) | ALOX5ADRB2ADRB1ADRB3MAOB | |
| SCHEMBL566991 | 0.83 | MAOB (0.60) | ALOX5ADRB2ADRB1ADRB3MAOB | |
| SCHEMBL11484008 | 0.81 | MTNR1A (0.56) | ALOX5ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL9695776 | 0.81 | ALOX5 (0.62) | ALOX5ADRB2ADRB1ADRB3HTT | |
| SCHEMBL9696268 | 0.80 | ALOX5 (0.62) | ALOX5ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL9696255 | 0.80 | ALOX5 (0.58) | ALOX5ADRB2ADRB1ADRB3HTT | |
| SCHEMBL9694802 | 0.80 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9696815 | 0.80 | ALOX5 (0.80) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-5120758-A | Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |