SCHEMBL9696056

SCHEMBL9696056

COC(=O)C(C)(O)C1COC(C)(C)O1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
CA2 P00918 2/20 0.32
HCRTR2 O43614 3/20 0.32
HCRTR1 O43613 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694546 1.00 L3MBTL1 (0.35) L3MBTL1CA2HCRTR2HCRTR1
SCHEMBL9696039 0.85 HCRTR2 (0.33) L3MBTL1CA2HCRTR2HCRTR1
SCHEMBL9695845 0.85 HCRTR2 (0.33) L3MBTL1CA2HCRTR2HCRTR1
SCHEMBL9696043 0.85 HCRTR2 (0.33) L3MBTL1CA2HCRTR2HCRTR1
SCHEMBL18341572 0.82 TMEM97 (0.33) CA2HCRTR2HCRTR1
SCHEMBL18341570 0.82 TMEM97 (0.33) CA2HCRTR2HCRTR1
SCHEMBL28595773 0.78 CA2 (0.32) CA2
SCHEMBL9696049 0.77 CA2 (0.33) CA2
SCHEMBL9695839 0.77 CA2 (0.33) CA2
SCHEMBL1487031 0.75 CA2 (0.34) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463470-A2 Process for the preparation of a fluorotetrahydrofuranone derivative F. HOFFMANN-LA ROCHE AG (CH) 1992-01-02 EP claimed
EP-0463470-A2 Process for the preparation of a fluorotetrahydrofuranone derivative F. HOFFMANN-LA ROCHE AG (CH) 1992-01-02 EP disclosed